Gene description for FLOT2
Gene name flotillin 2
Gene symbol FLOT2
Other names/aliases ECS-1
ECS1
ESA
ESA1
M17S1
Species Homo sapiens
 Experiment description of studies that identified FLOT2 in Lymphoma cells

1
Experiment ID3166
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL6 (GCB) - 48 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

2
Experiment ID3167
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB) - 48 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

3
Experiment ID3168
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY3 (ABC) - 48 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

4
Experiment ID3169
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY10 (ABC) - 48 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID3171
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL6 (GCB) - 72 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

6
Experiment ID3172
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB) - 72 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

7
Experiment ID3173
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY3 (ABC) - 72 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

8
Experiment ID3174
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY10 (ABC) - 72 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
ELISA
EV-TRACK -

9
Experiment ID3175
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameU2932 (ABC) - 72 h
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID3176
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID3177
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID3185
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL6 (GCB)-derived IgG2a control EVs
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

13
Experiment ID3186
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL6 (GCB)-derived CD20-positive EVs
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

14
Experiment ID3187
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL6 (GCB)-derived IgG2a control EVs
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

15
Experiment ID3188
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL6 (GCB)-derived CD20-positive EVs
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

16
Experiment ID3189
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

17
Experiment ID3190
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

18
Experiment ID3191
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

19
Experiment ID3192
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameSUDHL4 (GCB)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

20
Experiment ID3193
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY10 (ABC)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

21
Experiment ID3194
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY10 (ABC)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

22
Experiment ID3195
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY10 (ABC)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

23
Experiment ID3196
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Western blotting
PubMed ID 34743199   
OrganismHomo sapiens
Experiment descriptionCD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles
AuthorsAitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H.
Journal name Br J Cancer
Publication year2021
SampleLymphoma cells
Sample nameOCI-LY10 (ABC)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

24
Experiment ID1669
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34108659   
OrganismHomo sapiens
Experiment descriptionQuantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
AuthorsKugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R.
Journal name Nat Cell Biol
Publication year2021
SampleLymphoma cells
Sample nameRaji
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
Methods used in the studyRT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
EV-TRACK -

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